Serveur d'exploration sur la grippe au Canada

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Interim estimates of 2013/14 vaccine effectiveness against influenza A(H1N1)pdm09 from Canada s sentinel surveillance network, January 2014.

Identifieur interne : 000284 ( Main/Exploration ); précédent : 000283; suivant : 000285

Interim estimates of 2013/14 vaccine effectiveness against influenza A(H1N1)pdm09 from Canada s sentinel surveillance network, January 2014.

Auteurs : Dm Skowronski [Canada] ; C. Chambers ; S. Sabaiduc ; G. De Serres ; Ja Dickinson ; Al Winter ; K. Fonseca ; Jb Gubbay ; H. Charest ; M. Petric ; M. Krajden ; Sm Mahmud ; P. Van Caeseele ; Tl Kwindt ; A. Eshaghi ; N. Bastien ; Y. Li

Source :

RBID : pubmed:24524234

Descripteurs français

English descriptors

Abstract

The 2013/14 influenza season to date in Canada has been characterised by predominant (90%) A(H1N1)pdm09 activity. Vaccine effectiveness (VE) was assessed in January 2014 by Canada's sentinel surveillance network using a test-negative case-control design. Interim adjusted-VE against medically-attended laboratory-confirmed influenza A(H1N1)pdm09 infection was 74% (95% CI: 58-83). Relative to vaccine, A(H1N1)pdm09 viruses were antigenically similar and genetically well conserved, with most showing just three mutations across the 50 amino acids comprising antigenic sites of the haemagglutinin protein.

DOI: 10.2807/1560-7917.es2014.19.5.20690
PubMed: 24524234


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<div type="abstract" xml:lang="en">The 2013/14 influenza season to date in Canada has been characterised by predominant (90%) A(H1N1)pdm09 activity. Vaccine effectiveness (VE) was assessed in January 2014 by Canada's sentinel surveillance network using a test-negative case-control design. Interim adjusted-VE against medically-attended laboratory-confirmed influenza A(H1N1)pdm09 infection was 74% (95% CI: 58-83). Relative to vaccine, A(H1N1)pdm09 viruses were antigenically similar and genetically well conserved, with most showing just three mutations across the 50 amino acids comprising antigenic sites of the haemagglutinin protein.</div>
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<name sortKey="Sabaiduc, S" sort="Sabaiduc, S" uniqKey="Sabaiduc S" first="S" last="Sabaiduc">S. Sabaiduc</name>
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<country name="Canada">
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<name sortKey="Skowronski, Dm" sort="Skowronski, Dm" uniqKey="Skowronski D" first="Dm" last="Skowronski">Dm Skowronski</name>
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</record>

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{{Explor lien
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   |texte=   Interim estimates of 2013/14 vaccine effectiveness against influenza A(H1N1)pdm09 from Canada s sentinel surveillance network, January 2014.
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